Medina is a comic book artist known for his work for various comic book companies, including Megaton Comics, First Comics, Marvel Comics, & Image Comics.
Medina began his career illustrating such titles as Berserker and Megaton at Megaton Comics, before starting to work for Marvel Comics on The Incredible Hulk, Warlock and the Infinity Watch, Blackwulf, Avengers, The Amazing Spider-Man, & Marvel Knights Spider-Man.  He then worked for Image Comics, illustrating Sam and Twitch, a spinoff of the title Spawn & later illustrated Spawn itself and Kiss: Psycho Circus, based on the rock music group Kiss.